The Big Bang Theory. I think that’s pretty self explanatory. In case it’s not:
Sheldon is beyond obnoxious, Leonard is a jackass, Raj is a coward, Howard is nowhere near as smooth as he thinks he is, and Penny is a first grade moron. The characters are some of the worst I’ve ever seen, but for some misbegotten reason, I actually bought a bunch of seasons and binged it a few times.
That’s a good number of brain cells I can never get back.